(2,2′-Bipyridine)dichlorogold(III) nitrate

IL 22 ( interleukin 22 )

A22 22..22

Four randomised controlled trials (RCTs) and one RCT metaanalysis are featured in the Journal this month. The latter is a review of trials of newer-generation antidepressants and cognitive–behavioural therapy (CBT) for adolescent depression (Dubicka et al, pp. 433–440). In an area of clinical practice plagued by controversy, the authors of this review were able to contribute the finding that ad...

A22 22..22

Three papers in the Journal this month consider issues related to measuring, understanding and treating mental ill health in childhood. Baron-Cohen et al (pp. 500–509) undertook a study to establish the prevalence of autism-spectrum conditions in Cambridgeshire using two case ascertainment methods. First, a survey of individuals on the Special Educational Needs register and second, a screening ...

COMMENTARY Aminoethyl nitrate – the novel super nitrate?

Long-term use of most organic nitrates is limited by development of tolerance, induction of oxidative stress and endothelial dysfunction. In this issue of the BJP, Schuhmacher et al. characterized a novel class of organic nitrates with amino moieties (aminoalkyl nitrates). Aminoethyl nitrate was identified as a novel organic mononitrate with high potency but devoid of induction of mitochondrial...

Peroxyacetyl nitrate (PAN) and peroxypropionyl nitrate (PPN)

Atmospheric Chemistry and Physics Discussions This discussion paper is/has been under review for the journal Atmospheric Chemistry and Physics (ACP). Please refer to the corresponding final paper in ACP if available. Abstract Peroxyacetyl nitrate (PAN) and peroxypropionyl nitrate (PPN) were measured sequentially in situ by an online gas-phase chromatograph with electron capture detector at urba...